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Autonomic Regulation Trial (ART)
Goal: Validation of a new meassure for the assessment of
baroreflex function
Design: prospective cohort study, 1,000 post myocardial infarction
patients, minimum follow-up period one year
Methods: simultaneous recording of ECG, continuous arterial
pressure and respiration
ISAR-HRT2
Goal: Validation of primary defibrillator prophylaxis
Design: prospective, randomized and open-label therapy
study, 1,000 post myocardial infarction patients, minimal
follow-up 1.5 years
Methods: Risk stratification by means of left ventricular
ejection fraction and heart rate turbulence slope
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